It is safe and effective–many patients with severe, drug-resistant epilepsy show improvement. Huttenlocher PR. Rights and permissions Reprints and Permissions. The worst case scenario assumes that all of this weight is made of carbohydrates. Biochem Biophys Res Commun ; Table 1. Takeoka, J. However it should be recognised that abrupt loss of ketosis can significantly exacerbate seizure control. Filloux, S.
This can be altered by medication prescribed for the epileptic syndrome or for intercurrent illnesses. The goal of this paper is to compile the carbohydrate and caloric content of commonly used medications in this population. We also tested a worst case scenario calculation based on the weight of the tablet. Results: We list the carbohydrate and caloric content of medications studied. Our worst case scenario gives an over-estimate in all cases, making adjustments based on this calculation in an emergency setting safe. Conclusion: We propose this list as a tool for physicians, dietitians, nurses and pharmacists. The list can easily be adjusted, based on local practices and reviewed periodically. The ketogenic diet is a form of treatment used in children, and sometimes adults, with refractory epilepsies or with significant adverse events secondary to the anticonvulsants. Some animal models show an increased seizure threshold during treatment with the diet. The diet is usually maintained for a minimum period of two to six months and, if associated with a significant improvement, is pursued for at least two years.
No sources of funding were used to assist in the preparation of this paper. Biosci Rep. Funding None. Launch Research Feed. View 3 excerpts, cites background. The medical ketogenic diet should be used under medical supervision. If unsure of ketone levels a finger prick can be performed and acceptable level is 2. Metabolism ; Multiple variations of ketogenic diets exist, but the most commonly prescribed are the classic ketogenic diet, the modified Atkins diet, the low-glycemic index treatment diet, the medium-chain triglyceride MCT diet, and the modified MCT diet Table 1 [ 4 ]. The carbohydrate content of tablets, including anticonvulsants and other concomitant drugs, can be difficult to manage for the physicians, nurses and pharmacists.